2-Piperidone → HCID 52917191, compound

HRID 1020186Notes

Reaction equation

HRID 1020186 reaction equation
[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15]O)=[N:13][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][C:18]1=[O:23]>>[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15][N:17]3[CH2:22][CH2:21][CH2:20][CH2:19][C:18]3=[O:23])=[N:13][CH:14]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 126652-PiperidoneHCID 57517077(5-Phenylethynyl-pyridin-2-yl)-methanol

Product 1

HCID 52917191HCID 52917191, compound

Procedure

The title compound, brown oil, MS: m/e=291.2 (M+H+), can be prepared in accordance with the general method of example 31, step 2 from (5-phenylethynyl-pyridin-2-yl)-methanol (example 31, step 1) and piperidin-2-one.

Sources & evidence

ORD record
ord-6bcc2cec95b34247a5def139d85f6eaa
Source dataset
uspto-grants-2014_05
Patent number
US08716316B2

Reaction notes

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