1-Phenylimidazolidin-2-one → HCID 52917113, compound
Reaction equation
[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15]O)=[N:13][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17]1([N:23]2[CH2:27][CH2:26][NH:25][C:24]2=[O:28])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:17]1([N:23]2[CH2:27][CH2:26][N:25]([CH2:15][C:12]3[CH:11]=[CH:10][C:9]([C:8]#[C:7][C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)=[CH:14][N:13]=3)[C:24]2=[O:28])[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1Participants
3
Procedure
The title compound, light yellow solid, MS: m/e=354.3 (M+H+), can be prepared in accordance with the general method of example 31, step 2 from (5-phenylethynyl-pyridin-2-yl)-methanol (example 31, step 1) and 1-phenyl-imidazolidin-2-one.
Sources & evidence
- ORD record
- ord-074b38c4a90b4fb5ba0fc26291e50457
- Source dataset
- uspto-grants-2014_05
- Patent number
- US08716316B2
Reaction notes
Loading…