HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyltetrahydropyrimidin-2(1H)-one → 1-Methyl-3-(5-phenylethynyl-pyridin-2-ylmethyl)-tetrahydro-pyrimidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyltetrahydropyrimidin-2(1H)-one | HCID 12867748 | — |
| Reactant | (5-Phenylethynyl-pyridin-2-yl)-methanol | HCID 57517077 | — |
| Product | 1-Methyl-3-(5-phenylethynyl-pyridin-2-ylmethyl)-tetrahydro-pyrimidin-2-one | HCID 52917195 | — |
Reaction Steps
The title compound, light yellow oil, MS: m/e=306.2 (M+H+), can be prepared in accordance with the general method of example 31, step 2 from (5-phenylethynyl-pyridin-2-yl)-methanol (example 31, step 1) and 1-methyl-tetrahydro-pyrimidin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716316B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-3b9084bcae3b4ad2b9f319ac47128031 |
| Source note | uspto-grants-2014_05 |