Cyclopropanesulfonyl chloride → HCID 58990844, compound

HRID 1020211Notes

Reaction equation

HRID 1020211 reaction equation
[NH2:1][C:2]1[C:3]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([Br:17])=[CH:13][C:12]=2[F:18])=[CH:4][C:5](=[O:9])[N:6]([CH3:8])[CH:7]=1.[CH:19]1([S:22](Cl)(=[O:24])=[O:23])[CH2:21][CH2:20]1>>[Br:17][C:14]1[CH:15]=[CH:16][C:11]([NH:10][C:3]2[C:2]([NH:1][S:22]([CH:19]3[CH2:21][CH2:20]3)(=[O:24])=[O:23])=[CH:7][N:6]([CH3:8])[C:5](=[O:9])[CH:4]=2)=[C:12]([F:18])[CH:13]=1

Participants

3

Reactant 2

HCID 2760919Cyclopropanesulfonyl chlorideHCID 58259896HCID 58259896, compound

Product 1

HCID 58990844HCID 58990844, compound

Procedure

5-Amino-4-(2-fluoro-4-bromophenylamino)-1-methylpyridin-2(1H)-one was reacted with cyclopropanesulfonyl chloride using the same procedure as described in step f of example 1 above, and purified by HPLC.

Workup

  1. custompurified by HPLC

Sources & evidence

ORD record
ord-930eb99301344a07960706717161cf4e
Source dataset
uspto-grants-2014_05
Patent number
US08716318B2

Reaction notes

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