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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1020214Generated: November 2, 2026

4-Bromo-2-fluoroaniline → 4-(4-Bromo-2-fluorophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

https://huagongshe.com/reaction/1020214

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-fluoroanilineHCID 123050—
Reactant4-Chloro-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acidHCID 11542965—
Product4-(4-Bromo-2-fluorophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acidHCID 11646090—

Reaction Steps

The title compound is prepared from 4-chloro-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid by the procedure described in step e for Example 5, using 4-bromo-2-fluoroaniline instead of 2-fluoro-4-iodoaniline The title compound is used for the next reaction without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716318B2
Source datasetuspto-grants-2014_05
ORD IDord-5a3a8ef8809a47d694a464c6f19c1c2e
Source noteuspto-grants-2014_05