2-Chloro-4-iodoaniline → HCID 58990829, compound

HRID 1020215Notes

Reaction equation

HRID 1020215 reaction equation
Cl[C:2]1[C:3]([C:11]([OH:13])=[O:12])=[CH:4][N:5]([CH3:10])[C:6](=[O:9])[C:7]=1[CH3:8].[Cl:14][C:15]1[CH:21]=[C:20]([I:22])[CH:19]=[CH:18][C:16]=1[NH2:17]>>[Cl:14][C:15]1[CH:21]=[C:20]([I:22])[CH:19]=[CH:18][C:16]=1[NH:17][C:2]1[C:3]([C:11]([OH:13])=[O:12])=[CH:4][N:5]([CH3:10])[C:6](=[O:9])[C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 2829302-Chloro-4-iodoanilineHCID 115429654-Chloro-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

Product 1

HCID 58990829HCID 58990829, compound

Procedure

The title compound is prepared from 4-chloro-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid by the procedure described in step e for Example 5, using 2-chloro-4-iodoaniline instead of 2-fluoro-4-iodoaniline. The title compound is used for the next reaction without further purification.

Sources & evidence

ORD record
ord-38df6024646547619bd6b9a17dd9a7e0
Source dataset
uspto-grants-2014_05
Patent number
US08716318B2

Reaction notes

Loading…