反应详情

Carbamate III (Example 4) (225 mg, 781 μmol) was stirred at ambient temperature with HCl/dioxane (4 M, 4 ml) for 18 hours. Volatiles were removed under reduced pressure and the residue was azeotroped several times with toluene. 1H NMR (300 MHz, CD3OD) δ 3.37 (s, 1H), 3.55-3.59 (m, 2H), 3.64-3.68 (m, 2H), 4.43 (s, 2H), 6.82 (s, 1H).

1. customVolatiles were removed under reduced pressure
2. customthe residue was azeotroped several times with toluene