Diisopropylethylamine → HCID 58598874, compound

Participants

Reaction Steps

Di-tert-butyl dicarbonate (0.43 g, 2.00 mmol) and DIEA (1.0 mL, 6.0 mmol) were added to a solution of 5-chloro-8-methylene-1,2,3,3a,8,8a-hexahydro-2-aza-cyclopenta[a]indene (2.0 mmol) in CH2Cl2 (10 mL) at 0° C. The reaction mixture was stirred for 2 hours at from 0° C. to room temperature, then quenched with aqueous HCl (10 mL, 0.1 M). The organic extracts were washed with brine, dried over MgSO4, and concentrated to afford the subtitle compound in quantitative yield. MS calculated for C17H20ClNO2+H: 306, observed: 306.

Provenance & Evidence