HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitropyridine → tert-Butyl 4-(5-aminopyridin-2-yl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Product | tert-Butyl 4-(5-aminopyridin-2-yl)piperazine-1-carboxylate | HCID 17999304 | — |
Reaction Steps
Intermediate B-11 was prepared by the general procedure for intermediate B-2, by using 2-chloro-5-nitropyridine and 1-BOC-piperazine as starting materials. LCMS (ESI) calcd for [M+1]+ 279.2. found 279.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716312B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-99d477917efe4f93b1d44bc6ec9f2023 |
| Source note | uspto-grants-2014_05 |