Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1020354Generated: November 4, 2026

Methyl iodide → 8-(5-Aminopyridin-2-yl)-2-methyl-2,8-diazaspiro[4,5]decan-1-one

https://huagongshe.com/reaction/1020354

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant2-Chloro-5-nitropyridineHCID 78308—
Reactant2,8-Diazaspiro[4.5]decan-1-oneHCID 22225011—
Product8-(5-Aminopyridin-2-yl)-2-methyl-2,8-diazaspiro[4,5]decan-1-oneHCID 58428953—

Reaction Steps

Intermediate B-20 was prepared by the general procedure for intermediate B-15, by using 2-chloro-5-nitropyridine, 2,8-diazaspiro[4,5]decan-1-one, and methyl iodide as starting materials. MS (M+1): 261.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716312B2
Source datasetuspto-grants-2014_05
ORD IDord-5306fbec1bfd40f0829eb7c267c6d3f0
Source noteuspto-grants-2014_05