2-Chloro-5-nitropyridine → HCID 58431708, compound

HRID 1020355Notes

Reaction equation

HRID 1020355 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][N:3]=1.[C:11]([N:18]1[CH2:24][CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1)([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12]>>[NH2:8][C:5]1[CH:6]=[CH:7][C:2]([N:21]2[CH2:22][CH2:23][CH2:24][N:18]([C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[CH2:19][CH2:20]2)=[N:3][CH:4]=1

Participants

3

Reactant 2

HCID 783082-Chloro-5-nitropyridineHCID 2756058Tert-butyl 1,4-diazepane-1-carboxylate

Product 1

HCID 58431708HCID 58431708, compound

Procedure

Intermediate B-21 was prepared by the general procedure for intermediate B-2, by using 2-chloro-5-nitropyridine and 1-BOC-homopiperazine as starting materials. MS (M+1): 293.

Workup

  1. customIntermediate B-21 was prepared by the general procedure for intermediate B-2

Sources & evidence

ORD record
ord-9ee88495ad42415bb01f02a60e23df7d
Source dataset
uspto-grants-2014_05
Patent number
US08716312B2

Reaction notes

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