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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1020358Generated: October 27, 2026

2-Chloro-5-nitropyridine → 6-(4-(Hydroxyphenylmethyl)piperidin-1-yl)pyridin-3-amine

https://huagongshe.com/reaction/1020358

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-nitropyridineHCID 78308—
ReactantPhenyl-piperidin-4-yl-methanolHCID 339086—
Product6-(4-(Hydroxyphenylmethyl)piperidin-1-yl)pyridin-3-amineHCID 57461803—

Reaction Steps

Intermediate B-24 was prepared by the general procedure for intermediate B-2, by using 2-chloro-5-nitropyridine and 4-(hydroxyphenylmethyl)piperidine as starting materials. MS (M+1): 284.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716312B2
Source datasetuspto-grants-2014_05
ORD IDord-961fd6fedff74b159f9cd52f0d34de7b
Source noteuspto-grants-2014_05