2-Chloro-5-nitropyridine → HCID 58429203, compound

HRID 1020360Notes

Reaction equation

HRID 1020360 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][N:3]=1.[O:11]=[C:12]1[CH2:18][CH2:17][NH:16][CH2:15][CH2:14][N:13]1[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[O:11]=[C:12]1[CH2:18][CH2:17][N:16]([C:2]2[N:3]=[CH:4][C:5]([NH2:8])=[CH:6][CH:7]=2)[CH2:15][CH2:14][N:13]1[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 783082-Chloro-5-nitropyridineHCID 53410082HCID 53410082, compound

Product 1

HCID 58429203HCID 58429203, compound

Procedure

Intermediate B-26 was prepared by the general procedure for intermediate B-2, by using 2-chloro-5-nitropyridine and hexahydro-5-oxo-4-(phenylmethyl)-1H-1,4-diazepine as starting materials. MS (M+1): 297.

Workup

  1. customIntermediate B-26 was prepared by the general procedure for intermediate B-2

Sources & evidence

ORD record
ord-a92337704f104ad8a254770c88ac8a27
Source dataset
uspto-grants-2014_05
Patent number
US08716312B2

Reaction notes

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