2-Fluorophenyl isocyanate → HCID 67390462, compound

Participants

Reaction Steps

Compound 40 was prepared by the general procedure for compound 8, by using compound 39 and 2-fluorophenylisocyanate as starting materials. 1H NMR (500 MHz, CDCl3) δ 8.15 (d, 1H, J=2.5 Hz), 8.10 (t, 1H, J=8 Hz), 7.90 (dd, 1H, J=2.5, 9 Hz), 7.50 (s, 1H), 7.10 (m, 2H), 7.00 (m, 1H), 6.60 (d, 1H, J=4 Hz), 6.55 (d, 1H, J=9 Hz), 4.10 (m, 2H), 3.90 (m, 2H), 3.75 (m, 4H), 3.45 (t, 2H, J=6.5 Hz), 3.05 (t, 1H, J=12 Hz), 2.75 (t, 1H, J=13 Hz), 2.10 (t, 2H, J=6 Hz), 1.90 (d, 1H, J=13 Hz), 1.80 (m, 2H), 1.65 (m, 1H), 1.20 (q, 1H, J=11.5 Hz), 1.00 (d, 3H, J=6.5 Hz). MS (M+1): 590.

Provenance & Evidence