2-Propanesulfonyl chloride → HCID 67390057, compound

Participants

Reaction Steps

Compound 53 was prepared by the general procedure for compound 46, by using compound 49 and isopropylsulfonyl chloride as starting materials. 1H NMR (500 MHz, DMSO-d6) δ 10.36 (br s, 1H), 8.63 (br s, 1H), 8.36 (br s, 1H), 7.97 (br d, 1H, J=9.1 Hz), 7.83 (dm, 1H, J=8.8 Hz), 4.12 (m, 2H), 3.87 (h, 1H, J=7.0 Hz), 3.07 (br t, 1H, J=13.0 Hz), 2.77 (t, 1H, J=11.8 Hz), 1.78 (m, 2H), 1.68 (m, 1H), 1.55 (m, 1H), 1.18 (d, 6H, J=7.0 Hz), 1.16 (m, 1H), 0.95 (d, 3H, J=6.6 Hz). MS (M+1): 500.

Provenance & Evidence