2,4,6-Trichlorobenzenesulfonyl chloride → HCID 86657484, compound

HRID 1020381Notes

Reaction equation

HRID 1020381 reaction equation
C[CH:2]1[CH2:7][CH2:6][CH2:5][N:4]([C:8]2[O:9][C:10]([C:17]([NH:19][C:20]3[CH:21]=[CH:22][C:23]([N:26]4[CH2:31][CH2:30][N:29](CC5C=C(C=CC=5)C(OC)=O)[C:28](=O)[CH2:27]4)=[N:24][CH:25]=3)=[O:18])=[C:11]([C:13]([F:16])([F:15])[F:14])[N:12]=2)[CH2:3]1.[Cl:44][C:45]1[CH:50]=[C:49]([Cl:51])[CH:48]=[C:47]([Cl:52])[C:46]=1[S:53](Cl)(=[O:55])=[O:54]>>[N:4]1([C:8]2[O:9][C:10]([C:17]([NH:19][C:20]3[CH:25]=[N:24][C:23]([N:26]4[CH2:31][CH2:30][N:29]([S:53]([C:46]5[C:47]([Cl:52])=[CH:48][C:49]([Cl:51])=[CH:50][C:45]=5[Cl:44])(=[O:55])=[O:54])[CH2:28][CH2:27]4)=[CH:22][CH:21]=3)=[O:18])=[C:11]([C:13]([F:14])([F:16])[F:15])[N:12]=2)[CH2:3][CH2:2][CH2:7][CH2:6][CH2:5]1

Participants

3

Reactant 2

HCID 5213352,4,6-Trichlorobenzenesulfonyl chlorideHCID 67391134HCID 67391134, compound

Product 1

HCID 86657484HCID 86657484, compound

Procedure

Compound 152 was prepared by the general procedure for compound 8, by using compound C-3 and 2,4,6-trichlorophenylsulfonyl chloride as the starting materials. LCMS (ESI) Rt=4.56 min, [M+1]+ 669.4.

Sources & evidence

ORD record
ord-90906594d77f4d12a8ea2a1af3a4bd5a
Source dataset
uspto-grants-2014_05
Patent number
US08716312B2

Reaction notes

Loading…