HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoro-4-methylbenzeneboronic acid → HCID 49800567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoro-4-methylbenzeneboronic acid | HCID 2782674 | — |
| Reactant | HCID 49803713 | HCID 49803713 | — |
| Product | HCID 49800567 | HCID 49800567 | 38% |
Reaction Steps
The procedure of Example 2 was repeated except for using N-(2-aminophenyl)-4-((4-bromo-1-oxoisoindolin-2-yl)methyl)benzamide obtained in Example 9 instead of N-(2-aminophenyl)-4-((4-bromo-5,6-dimethoxy-1-oxoisoindolin-2-yl)methyl)benzamide, and 3-fluoro-4-methylphenyl boronic acid instead of phenyl boronic acid, to obtain the title compound (38%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716326B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-9744a6dad1fa4e349c8005909222bbe0 |
| Source note | uspto-grants-2014_05 |