HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 66689222, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methyl 6-aminohexanoate hydrochloride | HCID 11499324 | — |
| Reactant | Methyl 3-bromo-2-(bromomethyl)benzoate | HCID 21907554 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 66689222 | HCID 66689222 | 99% |
Reaction Steps
The procedure of the step 2 in Example 1 was repeated except that methyl 3-bromo-2-(bromomethyl)benzoate instead of methyl 3-bromo-2-(bromomethyl)-4,5-dimethoxybenzoate, methyl 6-aminohexanoate hydrochloride instead of methyl 4-(aminomethyl)benzoate hydrochloride, triethylamine (2.4 equiv.), and THF as a solvent were used and the reaction was conducted for 20 hrs, to obtain the title compound (99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716326B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-a369d58c3a0f4fab8edbc3fceeb5a405 |
| Source note | uspto-grants-2014_05 |