HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 66690111, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2,4-Dimethoxybenzeneboronic acid | HCID 2734341 | — |
| Reactant | HCID 65544462 | HCID 65544462 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | HCID 66690111 | HCID 66690111 | 80% |
Reaction Steps
The procedure of the step 1 in Example 92 was repeated except that the methyl 6-(3-bromo-2-methylbenzamido)hexanoate (34 mg, 0.10 mmol), tetrakis(triphenylphosphin)palladium (12 mg, 0.010 mmol), sodium carbonate (21 mg, 0.20 mmol), and 2,4-dimethoxyphenyl boronic acid (27 mg, 0.15 mmol) instead of phenyl boronic acid were dissolved in 3 mL of dioxane/H2O (4:1, v/v) to obtain the title compound (31 mg, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716326B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-e7e8e8e16ff549b483d0593af8770c7c |
| Source note | uspto-grants-2014_05 |