Hydrochloric Acid → HCID 49820725, compound

Participants

Reaction Steps

To the ice cold solution of 4-(2-benzylamino-quinoxalin-6-yl)-pyrazole-1-carboxylic acid tert-butyl ester (157 mg, 0.39 mmol) in 1,4-dioxane (3 mL) was added 14% HCl in dioxane (2 mL). The resulting mixture was stirred at RT for 2 hrs. After completion of reaction the volatiles were evaporated off under vacuum and the HCl salt was triturated with DCM to obtain crude product. The crude was further purified by prep-HPLC to afford the title compound (32 mg, 27%).

Provenance & Evidence