HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-methylbenzo[c][1,2]oxaborole-1,5(3H)-diol → 5-Chloro-6-(1-hydroxy-7-methyl-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)-2-(2-isopropoxyethoxy)nicotinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-methylbenzo[c][1,2]oxaborole-1,5(3H)-diol | HCID 58079868 | — |
| Reactant | 5,6-Dichloro-2-(2-isopropoxyethoxy)nicotinonitrile | HCID 86661720 | — |
| Product | 5-Chloro-6-(1-hydroxy-7-methyl-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)-2-(2-isopropoxyethoxy)nicotinonitrile | HCID 66726657 | — |
Reaction Steps
This compound was prepared from 5,6-dichloro-2-(2-isopropoxyethoxy)nicotinonitrile and 7-methylbenzo[c][1,2]oxaborole-1,5(3H)-diol in a similar manner to that of D230. 1H-NMR (400 MHz, DMSO-d6) δ (ppm) 1.02 (d, J=4.8 Hz, 6H), 2.44 (s, 3H), 3.45-3.56 (m, 3H), 4.21-4.23 (m, 2H), 5.02 (s, 2H), 7.03 (s, 1H), 7.11 (s, 1H), 8.58 (s, 1H), 10.0 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716478B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-60accf4ebb054a70a7df029d0a4a4697 |
| Source note | uspto-grants-2014_05 |