Lithium borohydride → HCID 67274069, compound

Participants

Reaction Steps

To 216 mg (0.758 mmol) of the ester from step 1 in 5 mL THF at 0° C. was added 455 μL (0.91 mmol, 1.2 eq) of LiBH4 solution (1M THF) and the reaction was stirred at room temperature overnight. The reaction was quenched with 1N HCl, extracted with EtOAc, washed with H2O, aqueous NaCl solution, dried (Mg SO4), and concentrated in vacuo to yield 167 mg (91%) of 2-(2-cyclopent-1-enyl-1H-indol-4-yloxy)-ethanol.

Provenance & Evidence