反应详情

Methyl hydrazine (750 mg, 16.30 mmol) was added to a solution of Methyl 6-chloronicotinimidate (1BX) (2.6 g, 15.29 mmol) in Pyridine (10 ml) at room temperature, then stirred for 1 hour. The solvent was evaporated, and residual solid triturated with cold Ether (2×10 ml) yielding title product 2BX as a yellow powder (2.4 g, 85%) MS (MH, 185)

1. customThe solvent was evaporated
2. customresidual solid triturated with cold Ether (2×10 ml)