HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 3-(3-Bromo-2-fluorophenyl)-3-hydroxypropanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 3-Bromo-2-fluorobenzaldehyde | HCID 22019361 | — |
| Product | 3-(3-Bromo-2-fluorophenyl)-3-hydroxypropanenitrile | HCID 66743223 | — |
Reaction Steps
Reaction of 3-bromo-2-fluorobenzaldehyde with acetonitrile gave 3-(3-bromo-2-fluorophenyl)-3-hydroxypropanenitrile as a light yellow oil. 1H NMR (400 MHz, CDCl3) δ 7.54 (t, J=7.2 Hz, 2H), 7.11 (td, J=7.6, 0.4 Hz, 1H), 5.37 (dd, J=6.8, 4.4 Hz, 1H), 2.73-2.91 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716529B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-2c4b9740744d4cbf8f5871b4af69e04c |
| Source note | uspto-grants-2014_05 |