Potassium Carbonate → HCID 86762385, compound

Participants

Reaction Steps

N-([1,1′-biphenyl]-4-yl)[1,1′:3′,1″-terphenyl]-2′-amine (15.9 g, 40.0 mmol), 4-iodoanisole (37.4 g, 160.0 mmol), potassium carbonate (22.1 g, 160.0 mmol), copper powder (5.1 g, 80.0 mmol), 18-crown-6 ether (21.1 g, 80.0 mmol) and 1,2-dichlorobenzene (200 mL) were bubbled with nitrogen for 30 min. The mixture was refluxed for 72 h. After cooling, the reaction mixture was filtered through a silica pad and washed with toluene (containing 0.5% triethylamine). The solvent was removed in vacuo and the residue was purified by flash chromatography using 40-50% toluene/hexane (containing 0.5% triethylamine) to afford N-([1,1′-biphenyl]-4-yl)-N-(4-methoxyphenyl)-[1,1′:3′,1″-terphenyl]-2′-amine (10.3 g, 51% yield) as a white solid.

Provenance & Evidence