HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethoxypiperidin-4-one → 4-Amino-1-ethoxy-piperidine-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethoxypiperidin-4-one | HCID 57096529 | — |
| Reactant | 4-Amino-1-methoxy-piperidine-4-carbonitrile | HCID 59614594 | — |
| Product | 4-Amino-1-ethoxy-piperidine-4-carbonitrile | HCID 59614603 | — |
Reaction Steps
4-Amino-1-ethoxy-piperidine-4-carbonitrile is prepared analogously to the synthesis of 4-amino-1-methoxy-piperidine-4-carbonitrile (preparation example 1, Step 1) starting from N-ethoxy-4-piperidone (Journal of Organic Chemistry (1961), 26, 1867-74).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722578B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-45b521a1912d46cf8674c1ac9d950964 |
| Source note | uspto-grants-2014_05 |