N-(2-Hydroxyethyl)phthalimide → HCID 68661365, compound

Participants

Reaction Steps

In the same manner as in Synthesis Example 6, 500 mg of 2,6-dichloro-4-phenylquinazoline (compound No. Ia1-3) and 382 mg of N-(2-hydroxyethyl)phthalimide were reacted to obtain 380 mg of 6-chloro-4-phenyl-2-(2-phthalimidoethoxy)quinazoline. Mp. 154.7° C. 1H NMR (CDCl3): 4.25 (2H, t, J=5.8 Hz), 4.84 (2H, t, J=5.8 Hz), 7.53-7.60 (3H, m), 7.67-7.71 (3H, m), 7.72-7.76 (3H, m), 7.78-7.82 (2H, m), 7.97 (1H, d, J=2.2 Hz).

Provenance & Evidence