Hydrogen chloride-ethyl acetate → HCID 66975542, compound

Participants

Reaction Steps

To a solution of tert-butyl (6RS,7RS)-6-[(acetylamino)methyl]-7-(3,4-dichlorophenyl)-1,4-oxazepane-4-carboxylate (176 mg) in ethyl acetate (0.5 mL) was added 4 N hydrogen chloride-ethyl acetate solution (3 mL), and the mixture was stirred at room temperature for 2 hr. The crystals obtained by concentration under reduced pressure were recrystallized from ethanol-water to give the title compound (102 mg).

Provenance & Evidence