Ethanol hydrochloride → HCID 66976642, compound

Participants

Reaction Steps

To a solution of tert-butyl (6RS,7SR)-7-(3-chloro-4-fluorophenyl)-6-(hydroxymethyl)-1,4-oxazepane-4-carboxylate (81 mg) in ethanol (1 mL) was added 14.7 N hydrogen chloride-ethanol solution (2.0 mL), and the mixture was stirred at room temperature for 1 hr. The crystals obtained by concentration under reduced pressure were recrystallized from ethyl acetate-ethanol to give the title compound (48 mg).

Provenance & Evidence