HCID 66975384, compound → HCID 66975729, compound

Participants

Reaction Steps

A solution of (4SR)-4-[(1RS)-1-(3,4-dichlorophenyl)-2-nitroethyl]-2,2-dimethyl-1,3-dioxolane (12.16 g) and Raney-nickel (10 g) in ethanol (100 ml) was stirred under a hydrogen atmosphere at room temperature for 5 hr. The reaction mixture was filtered through celite, and the solvent of the filtrate was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (methanol/ethyl acetate) to give the title compound (3.40 g).

Provenance & Evidence