反应详情

To a solution of tert-butyl (6R,7R)-7-(3,4-dichlorophenyl)-6-{[(methoxyacetyl)amino]methyl}-1,4-oxazepane-4-carboxylate (161 mg) in ethanol (1 ml) was added 14.0 M hydrogen chloride-ethanol solution (2 mL), and the mixture was stirred at room temperature for 1 hr. The solvent was evaporated under reduced pressure. The obtained crystals were recrystallized from ethanol to give the title compound (125 mg) as colorless crystals.

1. customThe solvent was evaporated under reduced pressure
2. customThe obtained crystals were recrystallized from ethanol