HCID 86663862, compound → HCID 66975410, compound

Participants

Reaction Steps

To a solution of (2RS,3SR)—N-benzyl-3-(3,4-dichlorophenyl)-N-(2-hydroxyethyl)oxirane-2-carboxamide (42.2 g) in acetonitrile (350 ml) was added scandium(III)trifluoromethanesulfonate (5.67 g), and the mixture was stirred at room temperature for 20 min. The reaction mixture was concentrated under reduced pressure, and the residue was purified by silica gel chromatography (hexane/ethyl acetate) to give the title compound (31.0 g).

Provenance & Evidence