Ethyl isocyanate → HCID 66976464, compound

HRID 1022697Notes

Reaction equation

[NH2:1][CH2:2][CH:3]1[CH:9]([C:10]2[CH:15]=[CH:14][C:13]([Cl:16])=[C:12]([Cl:17])[CH:11]=2)[O:8][CH2:7][CH2:6][N:5](C(OC(C)(C)C)=O)[CH2:4]1.[CH2:25]([N:27]=[C:28]=[O:29])[CH3:26]>>[ClH:16].[Cl:17][C:12]1[CH:11]=[C:10]([CH:9]2[O:8][CH2:7][CH2:6][NH:5][CH2:4][CH:3]2[CH2:2][NH:1][C:28]([NH:27][CH2:25][CH3:26])=[O:29])[CH:15]=[CH:14][C:13]=1[Cl:16]

Participants

Reactant 2

HCID 8022Ethyl isocyanate

HCID 66975023HCID 66975023, compound

Product 1

HCID 66976464HCID 66976464, compound

Procedure

Using tert-butyl (6RS,7RS)-6-(aminomethyl)-7-(3,4-dichlorophenyl)-1,4-oxazepane-4-carboxylate and ethyl isocyanate, and in the same manner as in Example 3, the title compound was obtained.

Sources & evidence

ORD record: ord-f6661e9bce2540189c362185b8568f3b
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08722662B2

Reaction notes

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