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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1022820Generated: November 2, 2026

3-Chloro-2-hydroxypyridine → HCID 66976769, compound

https://huagongshe.com/reaction/1022820

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-2-hydroxypyridineHCID 582210—
Reactanttert-butyl (6S,7R)-7-(4-chloro-3-fluorophenyl)-6-{[(methylsulfonyl)oxy]methyl}-1,4-oxazepane-4-carboxylateHCID 86663855—
ProductHCID 66976769HCID 66976769—

Reaction Steps

Using tert-butyl (6S,7R)-7-(4-chloro-3-fluorophenyl)-6-{[(methylsulfonyl)oxy]methyl}-1,4-oxazepane-4-carboxylate and 3-chloropyridin-2(1H)-one, and by a method similar to that in Example 31, steps C and E, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08722662B2
Source datasetuspto-grants-2014_05
ORD IDord-348be91966e848b3822d0b6619845f69
Source noteuspto-grants-2014_05