反应详情

0.61 mL (1.02 g, 7.6 mmol) of sulfuryl chloride were added to a solution of 1.0 g (6.9 mmol) of compound 7 in 30 mL of dichloromethane. Three drops diethyl ether were added and the reaction was stirred at room temperature for 5 h. The solvents were removed by distillation and the remainder was treated with aqueous NaHCO3 solution. The precipitate was filtered, washed with water and dried to give 1.1 g (89%) of compound 8 as a green-yellow solid.

1. customThe solvents were removed by distillation
2. additionthe remainder was treated with aqueous NaHCO3 solution
3. filtrationThe precipitate was filtered
4. washwashed with water
5. customdried