HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57646762, compound → HCID 15604837, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57646762 | HCID 57646762 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15604837 | HCID 15604837 | 85% |
Reaction Steps
20 mg of 4-[5-(4-Fluoro-phenyl)-3-(3,4,5-trimethoxy-phenylamino)-isoquinolin-6-yloxy]-piperidine-1-carboxylic acid tert-butyl ester (183) were dissolved in 5 ml of ethanol saturated with HCl (gaseous). The resulting mixture was stirred for 1 h, then the solvent was evaporated and the product collected. Yield: 85%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722671B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-6e936920c6404c07ba5db8a14acb25d2 |
| Source note | uspto-grants-2014_05 |