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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1023229Generated: November 1, 2026

2,2-Difluorocyclopropane-1-carboxylic acid → HCID 178523672, compound

https://huagongshe.com/reaction/1023229

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Difluorocyclopropane-1-carboxylic acidHCID 2782823—
ReactantHCID 178478587HCID 178478587—
ProductHCID 178523672HCID 178523672—

Reaction Steps

The title compound, white solid (5 mg, 15%), MS (ISP) m/z=436.3 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperazin-1-yl)-ethyl]-cyclohexylamine hydrochloride (Intermediate A) (25.8 mg, 0.070 mmol) and 2,2-difluorocyclopropanecarboxylic acid

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08722683B2
Source datasetuspto-grants-2014_05
ORD IDord-8c58166206fd4da688e1b648fd9caaa5
Source noteuspto-grants-2014_05