2-Hydroxyisobutyric acid → HCID 178459879, compound

Participants

Reaction Steps

The title compound, white solid (11.2 mg, 38.3%), MS (ISP) m/z=418.5 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperazin-1-yl)-ethyl]-cyclohexylamine hydrochloride (Intermediate A) (25.8 mg, 0.070 mmol) and 2-hydroxy-2-methylpropanoic acid.

Provenance & Evidence