3-Hydroxyisovaleric acid → HCID 178459209, compound

Participants

Reaction Steps

The title compound, white solid (15 mg, 49.7%), MS (ISP) m/z=432.4 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperazin-1-yl)-ethyl]-cyclohexylamine hydrochloride (Intermediate A) (25.8 mg, 0.070 mmol) and 3-hydroxy-3-methylbutanoic acid.

Provenance & Evidence