Oxane-4-carboxylic acid → HCID 178523682, compound

Participants

Reaction Steps

The title compound, white solid (29.5 mg, 81.6%), MS (ISP) m/z=444.3 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperazin-1-yl)-ethyl]-cyclohexylamine hydrochloride (Intermediate A) (30 mg, 81.5 mmol) and tetrahydro-2H-pyran-4-carboxylic acid.

Provenance & Evidence