Dibromomethane → Methyl 5-bromo-6-(4-chlorophenyl)pyrazine-2-carboxylate

HRID 102333Notes

Reaction equation

HRID 102333 reaction equation
[Br:27][CH2:28][Br:29].[CH2:19]([O:20][N:21]=[O:22])[CH2:23][CH:24]([CH3:25])[CH3:26].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]2)[c:8]([NH2:11])[n:9][cH:10]1.[CH3:30][Si:31]([CH3:32])([CH3:33])[Br:34]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]2)[c:8]([Br:27])[n:9][cH:10]1

Participants

5

Reactant 4

HCID 3024DibromomethaneHCID 8053Isoamyl NitriteHCID 76113BromotrimethylsilaneHCID 675046835-Amino-6-(4-chloro-phenyl)-pyrazine-2-carboxylic acid methyl ester

Product 1

HCID 86619571Methyl 5-bromo-6-(4-chlorophenyl)pyrazine-2-carboxylate

Sources & evidence

ORD record
ord-63649c5006e74c6c9bc2f86a256ed21a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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