Tert-Butyl hypochlorite → HCID 46206227, compound

Participants

Reaction Steps

To a solution of N,N,N-trimethyl-1-(4-methyl-2-oxooxazolidin-4-yl)methanaminium chloride (1.52 mmol) in MeOH (1 ml) was added, dropwise, tert-butylhypochlorite (250 uL, 2.10 mmol). The solution was stirred for 3 h, evaporated, and purified by preparatory HPLC (H2O/CH3CN) to afford the title compound as a yellow foam (115.6 mg, 0.475 mmol, 31% over two steps). 1H NMR (D2O, 400 MHz) δ 1.64 (s, 3H), 3.31 (s, 9H), 3.80 (d, J=15.2 Hz, 1H), 3.88 (d, J=14.8 Hz, 1H), 4.61 (d, J=9.6 Hz, 1H), 4.93 (d, J=10.0 Hz, 1H). ESI/APCI expected for C8H16ClN2O2+: 207.09. Found: 207 (M+).

Provenance & Evidence