Tert-Butyl hypochlorite → HCID 46202672, compound

Participants

Reaction Steps

To a solution of 2-((4-methyl-2-oxooxazolidin-4-yl)methylsulfonyl)ethanesulfonic acid (950 mg, 3.31 mmol) in MeOH (5 ml) was added, dropwise, tert-butylhypochlorite (500 ul, 4.2 mmol). The solution was stirred for 1 h, concentrated in vacuo, and purified by preparatory HPLC (H2O/MeOH) to afford the title compound as a clear oil (430.0 mg, 1.336 mmol, 40%). 1H NMR (D2O, 400 MHz) δ 1.60 (s, 3H), 3.3-3.4 (m, 2H), 3.6-3.7 (m, 2H), 3.80 (d, J=14.8 Hz, 1H), 3.96 (d, J=14.8 Hz, 1H), 4.47 (d, J=9.4 Hz, 1H), 5.05 (d, J=9.4 Hz, 1H). ESI/APCI expected for C7H12ClNO7S2: 320.97. Found: 320 (M−H+).

Provenance & Evidence