HCID 59355188, compound → HCID 59355176, compound

HRID 1023493Notes

Reaction equation

HRID 1023493 reaction equation
[CH3:1][N:2]([CH3:13])[CH2:3][CH2:4][NH:5][CH2:6][C:7]([CH3:12])([N+:9]([O-])=O)[CH3:8]>CO.[Ni].O>[CH3:13][N:2]([CH3:1])[CH2:3][CH2:4][NH:5][CH2:6][C:7]([CH3:8])([NH2:9])[CH3:12]

Participants

5

Reactant 1

HCID 59355188HCID 59355188, compound

Product 1

HCID 59355176HCID 59355176, compound

Reagents, catalysts & solvents 3

HCID 935NickelCatalystHCID 887MethanolSolventHCID 962WaterSolvent

Procedure

To a solution of N1,N1-dimethyl-N2-(2-methyl-2-nitropropyl)ethane-1,2-diamine (23.2 mmol) in MeOH (20 ml) was added a slurry of Raney Nickel in H2O (1 ml). The vessel was pressurized with H2 (500 psi) and the suspension stirred for 24 h. The mixture was filtered through Celite, then 0.45 um PTFE, and concentrated in vacuo. ESI/APCI (pos) expected for C8H21N3: 159.17. Found: 160 (MH+).

Workup

  1. filtrationThe mixture was filtered through Celite
  2. concentration0.45 um PTFE, and concentrated in vacuo

Sources & evidence

ORD record
ord-05cc1d1f75f842389e569eb09d38a6cb
Source dataset
uspto-grants-2014_05
Patent number
US08722715B2

Reaction notes

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