Tert-Butyl hypochlorite → HCID 46202339, compound

Participants

Reaction Steps

A solution of 2-(4,4-dimethyl-2-oxoimidazolidin-1-yl)-N,N,N-trimethylethanaminium acetate (0.428 mmol) in MeOH (2 ml) was cooled to 0° C. tert-Butylhypochlorite (100 ul, 0.84 mmol) was added, causing a white precipitate to form. The solution was stirred for 15 min, and another portion of tert-butylhypochlorite (100 ul, 0.84 mmol) was added. The solution was stirred for an additional 15 min, then concentrated in vacuo. The residue was purified by RP-HPLC (H2O/CH3CN) to afford the title compound as a white powder (74.7 mg, 0.276 mmol, 65%). 1H NMR (D2O, 400 MHz) δ 1.24 (s, 6H), 1.85 (s, 3H), 3.11 (s, 9H), 3.37 (s, 2H), 3.50 (m, 2H), 3.68 (m, 2H). 13C NMR (D2O, 100 MHz) δ 22.32, 27.01, 39.24, 55.38, 57.82, 62.40, 161.31, 180.46. ESI/APCI (pos) expected for C10H21ClN3O+: 234.14. Found: 234.

Provenance & Evidence