HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67236226, compound → HCID 61147393, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67236226 | HCID 67236226 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 61147393 | HCID 61147393 | 87% |
Reaction Steps
To a solution of 2-{[3-(1-methylethyl)phenyl]oxy}-5-nitropyrimidine (Intermediate 84, 520 mg) in methanol (50 mL) was added Pd/C (10% wt., 100 mg) and the mixture was stirred under H2 atmosphere for 3 hours. The resulting mixture was filtered through a pad of celite and the filtrate was concentrated under vacuum to afford the title compound (400 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722695B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-2e43d16dce0641fab65f9e7faa811612 |
| Source note | uspto-grants-2014_05 |