4-Propylaniline → HCID 67045729, compound

Participants

Reaction Steps

A solution of 95% 4-nitrophthalic acid anhydride (4.22 g, 20.7 mmol) and 4-propylaniline (2.81 g, 20.7 mmol) in acetic acid (86 ml) was refluxed by heating for 24 hours. The reaction solution was cooled to room temperature, and then added to ice water, and the deposited crystals were collected by filtration, and washed with water. The resulting crystals were purified by recrystallization (ethanol) to obtain 5-nitro-2-(4-propyl-phenyl)-isoindole-1,3-dione as pale yellow scaly crystals (5.89 g, yield: 91.4%).

Provenance & Evidence