HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 6-Nitro-2-(4-methoxyphenyl)-2,3-dihydro-isoindol-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | Methyl 2-(bromomethyl)-5-nitrobenzoate | HCID 14552709 | — |
| Product | 6-Nitro-2-(4-methoxyphenyl)-2,3-dihydro-isoindol-1-one | HCID 67045294 | — |
Reaction Steps
By using 2-bromomethyl-5-nitrobenzoic acid methyl ester and 4-methoxyaniline instead of 2-bromomethyl-6-nitro-benzoic acid methyl ester and aniline used in Example 25, synthesis was performed in the same manner as that of Example 25 to obtain 6-nitro-2-(4-methoxyphenyl)-2,3-dihydro-isoindol-1-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722723B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-73d3fb4aa363476d8bdab05410a57576 |
| Source note | uspto-grants-2014_05 |