HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1023701Generated: October 25, 2026
4-[[(6-chloropyridin-3-yl)methyl](methyl)amino]furan-2(5H)-one → Rotenone
https://huagongshe.com/reaction/1023701
Participants
| Role | Name | HCID | Charge |
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| Reactant | 4-[[(6-chloropyridin-3-yl)methyl](methyl)amino]furan-2(5H)-one | HCID 11550459 | — |
| Reactant | 4-{[(6-Chloropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5h)-one | HCID 16750561 | — |
| Reactant | Flupyradifurone | HCID 16752772 | — |
| Reactant | 4-[[(5,6-Dichloropyridin-3-yl)methyl](2-fluoroethyl)amino]furan-2(5H)-one | HCID 16752773 | — |
| Reactant | 4-{[(6-Fluoropyrid-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5h)-one | HCID 25102832 | — |
| Reactant | 4-[[(6-Chloro-5-fluoropyridin-3-yl)methyl](methyl)amino]furan-2(5h)-one | HCID 25191044 | — |
| Reactant | 4-[[(6-chloropyridin-3-yl)methyl](2-fluoroethyl)amino]furan-2(5H)-one | HCID 25227411 | — |
| Reactant | 4-{[(6-Bromopyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5h)-one | HCID 44609422 | — |
| Reactant | 4-{[(2-Chloro-1,3-thiazol-5-yl)methyl](2-fluoroethyl)amino}furan-2(5h)-one | HCID 46221888 | — |
| Reactant | 4-{[(6-Chloro-5-fluoropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5h)-one | HCID 46221889 | — |
| Reactant | [(6-Chloropyridin-3-yl)methyl](methyl)oxido-lambda4-sulphanylidenecyanamide | HCID 131730852 | — |
| Reactant | [1-(6-Chloropyridin-3-yl)ethyl](methyl)oxido-lambda4-sulphanylidenecyanamide | HCID 131730854 | — |
| Product | Rotenone | HCID 6758 | — |
Reaction Steps
4-{[(6-bromopyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one (known from WO 2007/115644), 4-{[(6-fluoropyrid-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one (known from WO 2007/115644), 4-{[(2-chloro-1,3-thiazol-5-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one (known from WO 2007/115644), 4-{[(6-chloropyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one (known from WO 2007/115644), 4-{[(6-chloropyrid-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one (known from WO 2007/115644), 4-{[(6-chloro-5-fluoropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-one (known from WO 2007/115643), 4-{[(5,6-dichloropyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one (known from WO 2007/115646), 4-{[(6-chloro-5-fluoropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-one (known from WO 2007/115643), 4-{[(6-chloropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-one (known from EP-A-0 539 588), 4-{[(6-chloropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-one (known from EP-A-0 539 588), [(6-chloropyridin-3-yl)methyl](methyl)oxido-λ4-sulphanylidenecyanamide (known from WO 2007/149134), [1-(6-chloropyridin-3-yl)ethyl](methyl)oxido-λ4-sulphanylidenecyanamide (known from WO 2007/149134) and its diastereomers (A) and (B)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08722717B2 |
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| Source dataset | uspto-grants-2014_05 |
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| ORD ID | ord-086296b8bc924278bea35637093bad31 |
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| Source note | uspto-grants-2014_05 |
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