HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Aminophenylacetic acid ethyl ester → Ethyl 4-[(4,5-diisopropylfuran-2-carbonyl)amino]phenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Aminophenylacetic acid ethyl ester | HCID 225219 | — |
| Reactant | 4,5-Diisopropylfuran-2-carboxylic acid | HCID 58420514 | — |
| Product | Ethyl 4-[(4,5-diisopropylfuran-2-carbonyl)amino]phenylacetate | HCID 67395279 | 86% |
Reaction Steps
In the same manner as that of Example 2, 4,5-diisopropylfuran-2-carboxylic acid (60 mg, 0.306 mmol) was condensed with ethyl 4-aminophenylacetate, and the resultant was purified by silica gel chromatography [hexane-ethyl acetate (4:1)] to obtain ethyl 4-[(4,5-diisopropylfuran-2-carbonyl)amino]phenylacetate (94 mg, 86%) as colorless needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722730B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-23dae1022f46482982c679f1078a40ed |
| Source note | uspto-grants-2014_05 |